Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders: A Systemic Review

19 Jul 2022

Abstract excerpt

BACKGROUND: Indoleamine 2,3-dioxygenase (IDO) activity is induced by cellular immune activation and therefore associated with inflammatory diseases, among others psychiatric disorders. This review aims to elucidate IDO activity reflected by kynurenine (KYN) to tryptophan (TRP) ratio in severe mental disorders. METHODS: A systematic literature search in MEDLINE and EMBASE was conducted targeting clinical trials in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder and Treatment
Share to Schizophrenia research and treatment
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35850653
DOI: 10.2174/1568026622666220718155616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Indoleamine 2,3-dioxygenase (IDO)-activity in Severe Psychiatric Disorders: A Systemic ReviewPMID 35850653Read ↗

The tryptophan catabolite or kynurenine pathway in a major depressive episode with melancholia, psychotic features and suicidal behaviors; a systematic review and meta-analysisSemantic proximity Read ↗

Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic PathwaySemantic proximity Read ↗

Phase-and disorder-specific differences in peripheral metabolites of the kynurenine pathway in major depression, bipolar affective disorder and schizophreniaSemantic proximity Read ↗

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and diseaseSemantic proximity Read ↗

Inflammation‐induced activation of the indoleamine 2,3‐dioxygenase pathway: Relevance to cancer‐related fatigueSemantic proximity Read ↗

Kynurenine Pathway of Tryptophan Metabolism in Neuropsychiatric Disorders: Pathophysiologic and Therapeutic ConsiderationsSemantic proximity Read ↗

The Kynurenine Pathway as a Convergent Hub Linking Toll-Like Receptor Signaling, Environmental Exposures, and Gut–Brain Axis Dysfunction in Neurodegenerative DiseasesSemantic proximity Read ↗

Redefining Roles: A Paradigm Shift in Tryptophan-Kynurenine Metabolism for Innovative Clinical ApplicationsSemantic proximity Read ↗

Role of indoleamine 2,3-dioxygenase in health and diseaseSemantic proximity Read ↗

Tryptophan kynurenine metabolism as a common mediator of genetic and environmental impacts in major depressive disorder: the serotonin hypothesis revisited 40 years later.Semantic proximity Read ↗

Neuroinflammation and the Kynurenine Pathway in CNS Disease: Molecular Mechanisms and Therapeutic ImplicationsSemantic proximity Read ↗

The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It ComplicatedSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.