Article
Comparative multi-omics analysis uncovers contrasting molecular profiles of canine and human thyroid carcinomas
2025-03-17
Abstract excerpt
Thyroid tumors represent 1-3% of canine cancers, with most tumors classified as follicular carcinomas and less frequently as medullary carcinomas. In comparison, only 10-15% of human thyroid cancers are follicular and 2% are medullary, with prevalent activating mutations in BRAF and NRAS, or RET, respectively. A cohort of canine thyroid carcinomas underwent histopathological (n=60 and paired molecular (n=30, WE...
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Identifiers and source
- Literature Corpus work
- 0698ea38-23fc-511e-82d2-fa348407a417
- DOI
- 10.1101/2025.03.14.643300