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Article

Genomic alterations in thyroid cancer: biological and clinical insights.

Nature reviews. Endocrinology - 1 Feb 2024

Landa Iñigo, Cabanillas Maria E

Abstract excerpt

Tumours can arise from thyroid follicular cells if they acquire driver mutations that constitutively activate the MAPK signalling pathway. In addition, a limited set of additional mutations in key genes drive tumour progression towards more aggressive and less differentiated disease. Unprecedented insights into thyroid tumour biology have come from the breadth of thyroid tumour sequencing data from patients and...

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Identifiers

PMID: 38049644
DOI: 10.1038/s41574-023-00920-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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