Article

Suppression of Ovarian Cancer Cell Proliferation is Associated with Upregulation of Cell-Matrix Adhesion Programs and Integrin-β4-Induced Cell Protection from Cisplatin

2025-02-15

Abstract excerpt

The role of extracellular matrix adhesion components in modulation of the treatment sensitivity of ovarian cancer (OC) cells is not well understood. Analysis of ovarian cancer TCGA gene expression data sets revealed an inverse correlation between genes involved in cell-cycle progression and extracellular matrix interactions including laminin-binding receptor integrin β4, a major component of extracellular matrix a...

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Literature Corpus work: 06927778-0651-5168-aa3d-4c7c743a83ad
DOI: 10.1101/2025.02.10.637535

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