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E-cadherin: A determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness

21 Sept 2017

Abstract excerpt

Ovarian cancer (OC) is the fifth cancer death cause in women worldwide. The malignant nature of this disease stems from its unique dissemination pattern. Epithelial-to-mesenchymal transition (EMT) has been reported in OC and downregulation of Epithelial cadherin (E-cadherin) is a hallmark of this process. However, findings on the relationship between E-cadherin levels and OC progression, dissemination and...

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PMID: 28934230
DOI: 10.1371/journal.pone.0184439

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