Article

Optimized pseudotyping conditions for the SARS-COV2 Spike glycoprotein

2020-05-29

Abstract excerpt

The SARS-COV2 Spike glycoprotein is solely responsible for binding to the host cell receptor and facilitating fusion between the viral and host membranes. The ability to generate viral particles pseudotyped with SARS-COV2 Spike is useful for many types of studies, such as characterization of neutralizing antibodies or development of fusion-inhibiting small molecules. Here we characterized the use of a codon-optimi...

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Literature Corpus work: 06703101-961c-55c8-b4b9-978bc6d7a5cf
DOI: 10.1101/2020.05.28.122671

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