Article

Increased Testicular Insulin-like Growth Factor 1 is Associated with Gonadal Activation by Recombinant Growth Hormone in Immature Rats

2021-08-27

Abstract excerpt

<title>Abstract</title> To understand the mechanism of precocious sexual maturation following prepubertal growth hormone (GH) therapy, the effects of recombinant human GH (rhGH) on the kisspeptin-gonadotropin-releasing hormone-luteinizing hormone (GnRH-LH) system in the hypothalamus-pituitary axis, systemic and testicular insulin-like growth factor-1 (IGF1), spermatogenesis and Leydig cell steroidogenesis, and...

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Literature Corpus work: 0607c9e8-81e3-5db7-a968-8ab1505fb4bd
DOI: 10.21203/rs.3.rs-829382/v1

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