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Sustained GnRH Agonism Alters Endocrine Dynamics and Pubertal Progression in Juvenile Rats

2026-06-29

Abstract excerpt

<h4>Purpose</h4> Gonadotropin releasing hormone (GnRH) agonists are clinically used to delay pubertal progression by suppressing the hypothalamic-pituitary-gonadal (HPG) axis. While GnRH agonists have long been used clinically, the developmental characterization of HPG axis suppression during puberty remains incompletely understood. Thus, we examined the effects of GnRH receptor agonism in juvenile rats. <h4>Hypo...

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Literature Corpus work
f6f85ea2-e268-5ed3-ac22-73c20f811f42
DOI
10.64898/2026.06.26.734882
Open publication

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Sustained GnRH Agonism Alters Endocrine Dynamics and Pubertal Progression in Juvenile RatsDOI 10.64898/2026.06.26.734882
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