Article
Sustained GnRH Agonism Alters Endocrine Dynamics and Pubertal Progression in Juvenile Rats
2026-06-29
Abstract excerpt
<h4>Purpose</h4> Gonadotropin releasing hormone (GnRH) agonists are clinically used to delay pubertal progression by suppressing the hypothalamic-pituitary-gonadal (HPG) axis. While GnRH agonists have long been used clinically, the developmental characterization of HPG axis suppression during puberty remains incompletely understood. Thus, we examined the effects of GnRH receptor agonism in juvenile rats. <h4>Hypo...
Topics
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- Birth, Development, and Health
- Endocrine Disruptors
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Syndromes and Imprinting
- Hypothalamic control of reproductive hormones
- Neuroendocrine regulation and behavior
- Ovarian function and disorders
- Reproductive Biology and Fertility
Identifiers and source
- Literature Corpus work
- f6f85ea2-e268-5ed3-ac22-73c20f811f42
- DOI
- 10.64898/2026.06.26.734882
