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Article

Minipuberty: Looking Back to Understand Moving Forward

18 Jan 2021

Abstract excerpt

Hypothalamic-pituitary-gonadal (HPG) axis activation occurs three times in life: the first is during fetal life, and has a crucial role in sex determination, the second time is during the first postnatal months of life, and the third is with the onset of puberty. These windows of activation recall the three windows of the "Developmental Origin of Health and Disease" (DOHaD) paradigm and may play a substantial...

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PMID: 33537266
DOI: 10.3389/fped.2020.612235

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