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Article

Molecular mechanisms of gonadotropin-releasing hormone receptor gene regulation.

Journal of the Society for Gynecologic Investigation - 1 Jan 2000

Norwitz E R, Jeong K H, Chin W W

Abstract excerpt

GnRH plays a critical role in regulating mammalian reproductive development and function. At the level of the anterior pituitary, GnRH binds to the GnRH receptor (GnRHR) on the cell surface of pituitary gonadotropes. Here, it activates intracellular signal transduction pathways to effect both the synthesis and intermittent release of the gonadotropins LH and FSH. These hormones then enter the systemic circulation...

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Share to Gene Expression Regulation
Share to Hormones
Share to Menstrual Cycle

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Pituitary Gland

Share to Promoter Regions, Genetic

Share to Receptors, LHRH

Share to Regulatory Sequences, Nucleic Acid

Source

Identifiers

PMID: 10486777
DOI: 10.1016/s1071-5576(99)00022-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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