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Effect of CYP2D6 and CYP2C19 genotypes on atomoxetine serum levels -- a study based on therapeutic drug monitoring data

2022-12-08

Abstract excerpt

Atomoxetine is mainly metabolized by CYP2D6 while CYP2C19 plays a secondary role. It is known that patients carrying genotypes encoding decreased/absent CYP2D6 metabolism obtain higher atomoxetine concentrations and are at increased risk of adverse effects. Here, we aimed to investigate the added effects of reduced-function CYP2C19 genotype on atomoxetine concentrations in real-world settings. Serum atomoxetine co...

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Identifiers and source

Literature Corpus work
0600f404-ac3d-5b05-b9ba-66de7e121532
DOI
10.22541/au.167050638.80828727/v1
Open publication

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Effect of CYP2D6 and CYP2C19 genotypes on atomoxetine serum levels -- a study based on therapeutic drug monitoring dataDOI 10.22541/au.167050638.80828727/v1
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