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Article

CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosages.

Acta psychiatrica Scandinavica - 1 Sept 2001

Kirchheiner J, Brøsen K, Dahl M L, Gram L F, Kasper S, Roots I, Sjöqvist F, Spina E, Brockmöller J

Abstract excerpt

OBJECTIVE: This review aimed to provide distinct dose recommendations for antidepressants based on the genotypes of cytochrome P450 enzymes CYP2D6 and CYP2C19. This approach may be a useful complementation to clinical monitoring and therapeutic drug monitoring. METHOD: Our literature search covered 32 antidepressants marketed in Europe, Canada, and the United States. We evaluated studies which had compared...

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Source

Identifiers

PMID: 11531654
DOI: 10.1034/j.1600-0447.2001.00299.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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