Article

Single Cell RNA sequencing reveals transitional states and signaling shifts in nephron progenitor cells of the late-gestation rhesus macaque kidney

2025-08-22

Abstract excerpt

<h4>Background</h4> Human nephrogenesis is complete at 34-36 weeks gestation, with 60% of nephrons forming during the third trimester through lateral branch nephrogenesis (LBN). Currently, no mechanism exists for LBN as there are no late gestation human kidney transcriptional datasets. We hypothesized that a differentiated but dividing population of nephron progenitor cells (NPCs) would contribute to the amplific...

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Literature Corpus work: 05fa15de-4011-5f37-bbb0-8ad8154d04df
DOI: 10.1101/2025.08.18.670897

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Single Cell RNA sequencing reveals transitional states and signaling shifts in nephron progenitor cells of the late-gestation rhesus macaque kidneyDOI 10.1101/2025.08.18.670897Read

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