Article

Synaptic dysfunction in the perirhinal cortex of the R6/1 mouse model of Huntington's disease

2004-01-01

Abstract excerpt

Huntington's disease (HD) is a fatal brain disorder characterised by a progressive motor, psychiatric and cognitive decline, often manifesting in midlife. Since the identification of the gene responsible for HD and the development of predictive testing, it has become apparent that asymptomatic patients often exhibit early cognitive deficits. In particular, an impairment in recognition memory that is evident prior...

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Literature Corpus work: 0597f9ab-8996-5484-b11a-941091f7fd5d
DOI: 10.21954/ou.ro.0000fa01

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