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A clinically relevant SLC2A1-associated malignant epithelial cell state predicts prognosis and immunotherapy response in lung adenocarcinoma

2026-04-03

Abstract excerpt

<title>Abstract</title> <p>Background Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality, with therapeutic resistance largely driven by unresolved malignant epithelial heterogeneity within the tumor microenvironment. However, the epithelial cell states that underlie poor prognosis and immunotherapy resistance remain incompletely defined. Methods We performed an integrative multi-omic...

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Literature Corpus work
0580914d-41e2-52fc-9967-0bb955b1337f
DOI
10.21203/rs.3.rs-9298986/v1
Open publication

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A clinically relevant SLC2A1-associated malignant epithelial cell state predicts prognosis and immunotherapy response in lung adenocarcinomaDOI 10.21203/rs.3.rs-9298986/v1
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