Article

Contractile force of transplanted cardiomyocytes contributes to heart function after injury

2021-11-23

Abstract excerpt

Transplantation of pluripotent stem cell-derived cardiomyocytes represents an innovative therapeutic strategy for heart failure. Studies in small and large animals have demonstrated functional recovery of left ventricular function after cardiomyocyte transplantation 1–4 , and first clinical studies are currently underway 5 . Yet, the mechanism of action underlying graft-induced benefit is unknown 6 . Here we de...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 057a18f9-b8ab-5e98-a6fd-612c6ab39539
DOI: 10.1101/2021.11.23.469715

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Contractile force of transplanted cardiomyocytes contributes to heart function after injuryDOI 10.1101/2021.11.23.469715Read

Contractility governs cardiomyocyte cell cycle activitySemantic proximity Read

Impulse initiation in engrafted pluripotent stem cell-derived cardiomyocytes can stimulate the recipient heartSemantic proximity Read

Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytesSemantic proximity Read

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cellsSemantic proximity Read

Force Measurements of Human Embryonic Stem Cell-Derived Cardiomyocytes in an In Vitro Transplantation ModelSemantic proximity Read

Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles.Semantic proximity Read

Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct ModelSemantic proximity Read

Cardiac Regenerative MedicineSemantic proximity Read