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Investigating the impact of anaesthesia and surgery on Alzheimer's disease and the potential therapeutic role of Statin

2016-01-01

Abstract excerpt

This study examines the impact of general anaesthesia, surgery and perioperative atorvastatin on Alzheimer's disease pathology in mice. A progressive neurodegenerative condition of complex aetiology, Alzheimer's is a common cause of dementia in humans but has no disease modifying treatment. Its long pre-symptomatic phase and lack of known biomarkers means asymptomatic individuals are exposed to modifiable risk fac...

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Literature Corpus work
0579e7af-821a-5908-a993-c4d34ffa3f7a
DOI
10.25560/58257
Open publication

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