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Tandemly repeated NBPF 3mer HOR copies (Olduvai triplets) in Neanderthal AltaiNea.hg19 assembly and two novel tandem arrays of NBPF 3mer HOR repeats in complete T2T-CHM13 assembly of human chromosome 1

2023-06-01

Abstract excerpt

It is known that the ~ 1.6 kb NBPF repeats are human specific and contributing to cognitive capabilities, with increasing frequency in higher order repeat 3mer HORs (Olduvai triplets). From chimpanzee to modern human there is a discontinuous jump from 0 to ~ 50 tandemly organized 3mer HORs. Here we investigate the structure of NBPF 3mer HORs in the Neanderthal genome assembly of Pääbo and collaborators, comparing...

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Literature Corpus work
056d73bd-f816-5d6b-9b04-b522285ec5d9
DOI
10.21203/rs.3.rs-2977977/v1
Open publication

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Tandemly repeated NBPF 3mer HOR copies (Olduvai triplets) in Neanderthal AltaiNea.hg19 assembly and two novel tandem arrays of NBPF 3mer HOR repeats in complete T2T-CHM13 assembly of human chromosome 1DOI 10.21203/rs.3.rs-2977977/v1
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