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Tandemly repeated NBPF 3mer HOR copies (Olduvai triplets) in Neanderthal AltaiNea.hg19 assembly and two novel tandem arrays of NBPF 3mer HOR repeats in complete T2T-CHM13 assembly of human chromosome 1

2023-05-15

Abstract excerpt

It is known that the ∼1.6 kb NBPF repeats are human specific and contributing to cognitive capabilities, with increasing frequency in higher order repeat 3mer HORs (Olduvai triplets). From chimpanzee to modern human there is a discontinuous jump from 0 to ∼50 tandemly organized 3mer HORs. Here we investigate the structure of NBPF 3mer HORs in the Neanderthal genome assembly of Pääbo and collaborators, comparing it...

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Literature Corpus work
9d6709aa-484b-5bd5-9328-a002f39e4401
DOI
10.1101/2023.05.15.540746
Open publication

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Tandemly repeated NBPF 3mer HOR copies (Olduvai triplets) in Neanderthal AltaiNea.hg19 assembly and two novel tandem arrays of NBPF 3mer HOR repeats in complete T2T-CHM13 assembly of human chromosome 1DOI 10.1101/2023.05.15.540746
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