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mRNA‐based chimeric antigen receptor T cell therapy: Basic principles, recent advances and future directions

2023-12-29

Abstract excerpt

Abstract Non‐viral vector chimeric antigen receptor (CAR)‐T cells have garnered increasing attention due to their ability to efficiently eradicate cancer cells while mitigating undesirable side effects. However, the current methods for engineering chimeric antigen receptor T (CAR‐T) cells employ viral vectors that result in permanent CAR expression and potentially severe negative impacts. As a solution to these ch...

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Literature Corpus work
05630a01-83b3-511d-8970-43a76d7b1c9a
DOI
10.1002/inmd.20230036
Open publication

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mRNA‐based chimeric antigen receptor T cell therapy: Basic principles, recent advances and future directionsDOI 10.1002/inmd.20230036
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