Article

AttentionPert: Accurately Modeling Multiplexed Genetic Perturbations with Multi-scale Effects

2024-02-07

Abstract excerpt

Genetic perturbations (i.e. knockouts, variants) have laid the foundation for our understanding of many diseases, implicating pathogenic mechanisms and indicating therapeutic targets. However, experimental assays are fundamentally limited in the number of perturbation conditions they can measure. Computational methods can fill this gap by predicting perturbation effects under unseen conditions, but accurately pred...

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Literature Corpus work: 05551f8d-ff43-5de6-bd4f-554b33738e68
DOI: 10.1101/2024.02.02.578656

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