Article

Genome-wide investigation of gene-cancer associations for the prediction of novel therapeutic targets in oncology

2020-01-31

Abstract excerpt

<h4>ABSTRACT</h4> A major cause of failed drug discovery programs is suboptimal target selection, resulting in the development of drug candidates that are potent inhibitors, but ineffective at treating the disease. In the genomics era, the availability of large biomedical datasets with genome-wide readouts has the potential to transform target selection and validation. In this study we investigate how computation...

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Literature Corpus work: 05496fa7-799d-5c5b-b5d7-14850c466656
DOI: 10.1101/2020.01.30.927285

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