Article

Clinical and Biological Stratification in 121,560 Antidepressant Prescription Trajectories using Unsupervised Modelling and Clustering

2024-12-20

Abstract excerpt

Major depressive disorder is a complex condition with diverse presentations and polygenic underpinnings. Leveraging large biobanks linked to primary care prescription data, we developed a data-driven approach based on antidepressant prescription trajectories for patient stratification and novel phenotype identification. We extracted quantitative prescription trajectories for 56,951 UK Biobank (UKB) and 64,609 Dani...

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Literature Corpus work: 050dfaac-ede0-5874-9270-13d192bc842f
DOI: 10.1101/2024.12.17.24319152

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