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Establishment and characterization of NCC-DFSP5-C1: a novel patient-derived dermatofibrosarcoma protuberans cell line

2023-11-25

Abstract excerpt

<title>Abstract</title> <p>Dermatofibrosarcoma protuberans (DFSP) is the most prevalent dermal sarcoma, characterized by the presence of the fusion of the collagen type I alpha 1 (COL1A1) gene with the platelet-derived growth factor beta chain (PDGFB) gene. Although PDGF receptor inhibitor imatinib mesylate was approved for the treating patients with unresectable or metastatic DFSP, disease progression was shown...

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Literature Corpus work
050b0dbf-1d45-5dbe-bd63-0274d4b00875
DOI
10.21203/rs.3.rs-3626798/v1
Open publication

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