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Genome-wide association analysis reveals extensive genetic overlap between mood instability and psychiatric disorders but divergent patterns of genetic effects

2021-07-19

Abstract excerpt

<h4>ABSTRACT</h4> Mood instability (MOOD) is a transdiagnostic phenomenon with a prominent neurobiological basis. Recent genome-wide association studies found significant positive genetic correlation between MOOD and major depression (DEP) and weak correlations with other psychiatric disorders. We investigated the polygenic overlap between MOOD and psychiatric disorders beyond genetic correlation to better charact...

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Literature Corpus work
04e65f46-6dc2-5ee4-b536-c80ba4271718
DOI
10.1101/2021.07.16.21260608
Open publication

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Genome-wide association analysis reveals extensive genetic overlap between mood instability and psychiatric disorders but divergent patterns of genetic effectsDOI 10.1101/2021.07.16.21260608
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