Article
A Model-Driven Quantitative Analysis of Retrotransposon Distributions in the Human Genome.
Genome biology and evolution - 3 Nov 2020
Riba Andrea, Fumagalli Maria Rita, Caselle Michele, Osella Matteo
Abstract excerpt
Retrotransposons, DNA sequences capable of creating copies of themselves, compose about half of the human genome and played a central role in the evolution of mammals. Their current position in the host genome is the result of the retrotranscription process and of the following host genome evolution. We apply a model from statistical physics to show that the genomic distribution of the two most populated classes...
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