Article

Alcohol use reduces the efficacy of anti-PD1 immunotherapy by disrupting anti-tumor immunity

2025-07-18

Abstract excerpt

Immune checkpoint inhibition (ICI) has improved clinical outcomes for certain patients with cancer. However, only a minority of patients have durable responses with underlying causes of differential immune responses across individuals often being unknown. Lifestyle exposures impact immune function and may subsequently alter the response to ICI. Alcohol use is common among cancer patients with known detrimental eff...

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Literature Corpus work: 04b9418e-71e6-582c-9650-ae64490b1005
DOI: 10.1101/2025.07.14.664729

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