Article

Salubrinal suppresses cadmium-induced cell death by affecting endoplasmic reticulum stress/autophagy in SH-SY5Y human neuroblastoma cells

2022-06-17

Abstract excerpt

<h4>Background: </h4> Salubrinal, inhibits the dephosphorylation of eukaryotic translation initiation factor 2 subunit α (eIF2α), provides protection against cadmium toxicity. However, underlying mechanisms of salubrinal for ER stress/autophagy remain unknown in SH-SY5Y human neuroblastoma cells following exposure to cadmium. <h4>Methods:</h4> Cells were exposed to 1.0 µM CdCl 2 and 10 µM salubrinal for 24 h. Cyto...

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Literature Corpus work: 047e9886-30e6-5904-9cae-afaff6a3b911
DOI: 10.21203/rs.3.rs-1759494/v1

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