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Article

Modelling cadmium-induced cardiotoxicity using human pluripotent stem cell-derived cardiomyocytes.

Journal of cellular and molecular medicine - 1 Sept 2018

Shen Jiaxi, Wang Xiaochen, Zhou Danni, Li Tongyu, Tang Ling, Gong Tingyu, Su Jun, Liang Ping

Abstract excerpt

Cadmium, a highly ubiquitous toxic heavy metal, has been widely recognized as an environmental and industrial pollutant, which confers serious threats to human health. The molecular mechanisms of the cadmium-induced cardiotoxicity (CIC) have not been studied in human cardiomyocytes at the cellular level. Here we showed that human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) can recapitulate the CIC at...

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Identifiers

PMID: 29993192
DOI: 10.1111/jcmm.13702
PMCID: PMC6111808

Genes

CIC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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