Article

Subtype-specific neutralizing antibodies promote antigenic shift during influenza virus co-infection

2025-08-08

Abstract excerpt

Reassortment between different influenza strains occurs when they co-infect the same host cell. The emergence of a reassortant virus depends on both its intrinsic fitness and extrinsic factors, including pre-existing humoral immunity. The generation of pandemic strains, such as H2N2 and H3N2, and zoonotic influenza A viruses, like H5N6, H5N8, and H7N9, in birds is suggested to be the result of extensive selection...

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Identifiers and source

Literature Corpus work: 046d3591-22ac-53eb-99ed-1cede0f92790
DOI: 10.1101/2025.08.08.669311

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