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Article

Escape From Monoclonal Antibody Neutralization Affects Henipavirus Fitness In Vitro and In Vivo.

The Journal of infectious diseases - 1 Feb 2016

Borisevich Viktoriya, Lee Benhur, Hickey Andrew, DeBuysscher Blair, Broder Christopher C, Feldmann Heinz, Rockx Barry

Abstract excerpt

Henipaviruses are zoonotic viruses that can cause severe and acute respiratory diseases and encephalitis in humans. To date, no vaccine or treatments are approved for human use. The presence of neutralizing antibodies is a strong correlate of protection against lethal disease in animals. However, since RNA viruses are prone to high mutation rates, the possibility that these viruses will escape neutralization...

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Identifiers

PMID: 26357909
DOI: 10.1093/infdis/jiv449
PMCID: PMC4704671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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