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Article

Neuraminidase-specific antibodies drive differential cross-protection between contemporary FLUBV lineages

28 Mar 2025

Abstract excerpt

The two influenza B virus (FLUBV) lineages have continuously diverged from each other since the 1980s, with recent (post-2015) viruses exhibiting accelerated evolutionary rates. Emerging data from human studies and epidemiological models suggest that increased divergence in contemporary viruses may drive differential cross-protection, where infection with Yamagata lineage viruses provides limited immunity against...

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PMID: 40153499
DOI: 10.1126/sciadv.adu3344

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