Article

Using bioinformatics for the identification of key peptides to engineer dopamine neurons. Towards a therapy for Parkinson’s disease.

2018-01-17

Abstract excerpt

Parkinson’s disease is a widespread condition caused by degeneration of dopamine neurons in the midbrain. A number of proteins are known to be important to signalling mechanisms present in the midbrain during natural dopamine neuron development, and may be utilised to better produce dopamine neurons in vitro . Relative expression levels of proteins were obtained from substantia nigra tissue of rats from embryonic...

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Literature Corpus work: 0428d396-c0d8-524d-a781-0997caee01d8
DOI: 10.7287/peerj.preprints.26443v2

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