Article

A Transcriptomic and Proteomic Atlas of Obesity and Type 2 Diabetes in Cynomolgus Monkeys

2021-12-13

Abstract excerpt

<h4>ABSTRACT</h4> Obesity and type 2 diabetes (T2D) remain major global healthcare challenges and developing therapeutics necessitate using nonhuman primate models. Here, we present transcriptomic and proteomic analyses of all the major organs of cynomolgus monkeys with spontaneous obesity or T2D in comparison to healthy controls. Molecular changes occur predominantly in the adipose tissues of individuals with ob...

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Literature Corpus work: 03e7dbd4-cbdf-5b0c-97a0-d7e5fd35389c
DOI: 10.1101/2021.12.10.472179

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