Article
Mediterranean Versus Western Diet Effects on Obesity Phenotypes and Adipose Tissue Transcriptional Profiles in Female Monkeys.
Obesity (Silver Spring, Md.) - 1 Mar 2026
Abusheikha Aya Jamal, Johnson Corbin S C, Snyder-Mackler Noah, Zimmerman Kip D, Frye Brett M, Shively Carol A, Register Thomas C
Abstract excerpt
OBJECTIVE: Obesity, or excessive body fat, is a significant health risk factor. Western diets (WD) contribute to metabolic dysfunction and obesity, while Mediterranean diets (MD) improve metabolic health. This study examined the contrasting effects of WD versus MD on visceral and subcutaneous adipose tissues (VAT, SAT) using a randomized preclinical trial in 38 female cynomolgus macaques assigned to consume...
Topics
- Animals
- Female
- Obesity
- Macaca fascicularis
- Diet, Mediterranean
- Diet, Western
- Intra-Abdominal Fat
- Transcriptome
- Insulin Resistance
- Subcutaneous Fat
- Phenotype