Back to search

Article

Duplication and overexpression of the genes encoding a beta 1,3-glucan synthase confer the intrinsic resistance to echinocandin in <i>Mucor circinelloides</i>

2022-01-03

Abstract excerpt

<h4>ABSTRACT</h4> Procedures such as solid organ transplants and cancer treatments can leave many patients in an immunocompromised state resulting in an increased susceptibility to opportunistic diseases including fungal infections. Mucormycosis infections are continually emerging and pose a serious threat to immunocompromised patients. Currently there has been a sharp increase in mucormycosis cases as a secondar...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
03d38307-526a-5678-bb15-aff8b5e4ba5e
DOI
10.1101/2022.01.03.474814
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Duplication and overexpression of the genes encoding a beta 1,3-glucan synthase confer the intrinsic resistance to echinocandin in <i>Mucor circinelloides</i>DOI 10.1101/2022.01.03.474814
Alternative ergosterol biosynthetic pathways confer antifungal drug resistance in the human pathogens within the <i>Mucor</i> species complexSemantic proximity
Micafungin exposure drives multidrug resistance in <i>Clavispora lusitaniae</i>Semantic proximity
A novel resistance pathway for calcineurin inhibitors in the human pathogenic Mucorales <i>Mucor circinelloides</i>Semantic proximity
New insights into the echinocandin resistance in <i>Candida</i> spp. in the clinical settingSemantic proximity
Recent Advances and Future Directions in the Understanding of MucormycosisSemantic proximity
Comparative genomics for the elucidation of multidrug resistance (MDR) in <i>Candida lusitaniae</i>Semantic proximity
A Novel Resistance Pathway for Calcineurin Inhibitors in the Human-Pathogenic Mucorales Mucor circinelloides.Semantic proximity
<i>CotH</i> genes are necessary for normal spore formation and virulence in <i>Mucor lusitanicus</i>Semantic proximity
Molecular mechanisms that govern infection and antifungal resistance in MucoralesSemantic proximity
<i>FKS1/2</i> -variant independent mechanisms underlying the emergence of resistance in echinocandin-refractory <i>Candida auris</i> infectionsSemantic proximity
Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides.Semantic proximity
A Mechanism Driving Echinocandin Heteroresistance in <i>Candida glabrata</i>Semantic proximity
Select a neighboring publication to make it the new centre.