Article

LRP6 modulates the phosphorylation of Cx43 via Gαs in ventricular tachycardia of myocardial infarction

2022-05-27

Abstract excerpt

<h4>Background: </h4> Ventricular tachycardia (VT) and ventricular fibrillation are the most causes of early death in patients with myocardial infarction (MI). This study was aimed to explore whether LRP6 and its upstream genes circRNA1615 and miR-152-3p modulated the phosphorylation of Connexin-43 (Cx43) via Gαs in VT of MI. Method we constructed the hypoxia cardiomyocyte model and AMI mice, and explored the modu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 03bdccea-f01c-539b-9710-fa446af887f1
DOI: 10.22541/au.165366258.81503280/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

LRP6 modulates the phosphorylation of Cx43 via Gαs in ventricular tachycardia of myocardial infarctionDOI 10.22541/au.165366258.81503280/v1Read

LRP6 modulates the phosphorylation of Cx43 via Gαs in ventricular tachycardia of myocardial infarctionSemantic proximity Read

CircRNA1615 Inhibits Ferroptosis via Modulation of Autophagy by the miRNA152-3p/LRP6 Axis in Cardiomyocytes of Myocardial InfarctionSemantic proximity Read

Network construction of aberrantly expressed miRNAs and their target mRNAs in ventricular myocardium with ischemia–reperfusion arrhythmiasSemantic proximity Read

LRRK2 Deficiency Protects Hearts from Myocardial Infarction Injury in Mice via the P53/HMGB1 PathwaySemantic proximity Read

Valtrate attenuates arrhythmia after myocardial ischemia-reperfusion via inducing N-linked glycosylation modification of LTβR to suppress TNFSF14-induced reduction of Cx43Semantic proximity Read

NR_027324 regulates autophagy and apoptosis by combining with miR-103-3p as ceRNA to regulate ATG5 in cardiomyocytes during hypoglycemic and hypoxic injurySemantic proximity Read

METTL3 drives heart failure by regulating Spp1 and Fos m6A modification in myocardial infarctionSemantic proximity Read

Pan-cancer analyses reveal genomics and clinical characteristics of the down regulated genes for recurrent myocardial infarction in cancerSemantic proximity Read

MicroRNA and mRNA Signatures in Ischemia Reperfusion Injury in Heart TransplantationSemantic proximity Read

LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR‐133b in myocardial fibrosis after myocardial infarctionSemantic proximity Read

Aerobic exercise-induced up-regulation of HIF-1α ameliorates heart failure by regulating MCT1 and MPC1 expressionSemantic proximity Read

Microarray Analysis Reveals a Potential Role of lncRNA Expression in remote ischemic preconditioning in Myocardial ischemia-reperfusion injurySemantic proximity Read