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Article

MicroRNA and mRNA Signatures in Ischemia Reperfusion Injury in Heart Transplantation

20 Nov 2013

Abstract excerpt

Ischemia reperfusion (I/R) injury is an unavoidable event occurring during heart transplantation, leading to graft failures and lower long-term survival rate of the recipient. Several studies have demonstrated that microRNAs (miRNAs) are vital regulators of signalling pathways involved in I/R injury. The present study aims to quantify the altered expression levels of miRNA and mRNA upon I/R injury in a mouse...

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PMID: 24278182
DOI: 10.1371/journal.pone.0079805

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