Article

Genomics of fetal haemoglobin: a targeted approach for reticulocyte transcriptome study

2023-06-30

Abstract excerpt

<h4>Background: </h4> Fetal haemoglobin (HbF) remains a major sickle cell disease modifier. The mechanism of HbF synthesis has been studied for several decades with the intention of increasing interventions for sickle cell disease (SCD), including drugs. However, the complex mechanism of HbF synthesis is influenced by multiple genetic factors interacting with environmental factors. In order to capture useful genet...

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Literature Corpus work: 0393f068-b166-569d-9819-041cd52b04e8
DOI: 10.21203/rs.3.rs-3061395/v1

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