Article

Regulation of CHD2 expression by the <i>Chaserr</i> long noncoding RNA is essential for viability

2019-01-31

Abstract excerpt

Genomic loci adjacent to genes encoding for transcription factors and chromatin remodelers are enriched for long non-coding RNAs (lncRNAs), but the functional importance of this enrichment is largely unclear. Chromodomain helicase DNA binding protein 2 ( Chd2 ) is a chromatin remodeller with various reported functions in cell differentiation and DNA damage response. Heterozygous mutations in human CHD2 have been...

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Literature Corpus work: 036e43af-f54a-5b33-b106-62176bc0fe4a
DOI: 10.1101/536771

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