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Integrating Bioinformatics and Machine Learning to Identify Mitochondria-Related Biomarkers and Their Association with Immune Infiltration in BK polyomavirus-associated nephropathy

2025-07-08

Abstract excerpt

BK polyomavirus-associated nephropathy (BKPyVAN) is a serious complication of kidney transplantation. Numerous kidney diseases such as BKPyVAN have been shown to cause mitochondrial dysfunction. This study aims to identify key mitochondria-related genes in BKPyVAN. We merged two datasets, GSE72925 and GSE47199, to form a training set after batch-effect removal. Hub mitochondria-related genes in BKPyVAN were identi...

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Literature Corpus work: ae04c4bd-def1-5190-9dab-1a97b6ed6e91
DOI: 10.1101/2025.07.07.25331061

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