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Evolving Perspectives on Innate Immune Mechanisms of IPF

9 Aug 2021

Abstract excerpt

While epithelial-fibroblast interactions are viewed as the primary drivers of Idiopathic Pulmonary Fibrosis (IPF), evidence gleaned from animal modeling and human studies implicates innate immunity as well. To provide perspective on this topic, this review synthesizes the available data regarding the complex role of innate immunity in IPF. The role of substances present in the fibrotic microenvironment including...

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PMID: 34434962
DOI: 10.3389/fmolb.2021.676569

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