Article

Direct estimation of mutations in great apes reveals significant recent human slowdown in the yearly mutation rate

2018-03-23

Abstract excerpt

The human mutation rate per generation estimated from trio sequencing has revealed an almost linear relationship with the age of the father and the age of the mother. The yearly trio-based mutation rate estimate of ~0.43×10 −9 is markedly lower than prior indirect estimates of ~1×10 −9 per year from phylogenetic comparisons of the great apes. This suggests either a slowdown over the past 10 million years or an i...

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Literature Corpus work: 02cb4979-588a-527c-ad97-9f14846f6c02
DOI: 10.1101/287821

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