Direct estimate of the spontaneous germ line mutation rate in African green monkeys.

Abstract excerpt

Here, I provide the first direct estimate of the spontaneous mutation rate in an Old World monkey, using a seven individual, three-generation pedigree of African green monkeys. Eight de novo mutations were identified within ∼1.5 Gbp of accessible genome, corresponding to an estimated point mutation rate of 0.94 × 10-8 per site per generation, suggesting an effective population size of ∼12000 for the species. This...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chlorocebus aethiops
• Share to Evolution, Molecular
• Share to Genetic Variation