Chemical probes for GPCRs : investigating GPR119

Abstract excerpt

GPCRs are one of the most important classes of proteins within the arena of drug discovery and therapeutics. They are involved in transmitting external stimuli across the cell membrane to elicit intracellular responses that can alter gene activation, protein synthesis and messenger signalling that can be intrinsic to health and disease. GPR119 is a GPCR shown to be involved in glucose-dependent insulin secretion w...

Topics

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• Computational Drug Discovery Methods
• Drug Design
• Gene Expression Regulation
• Ligands
• Molecular Targeted Therapy
• Monoclonal and Polyclonal Antibodies Research
• Receptor Mechanisms and Signaling
• Receptors, G-Protein-Coupled

Identifiers and source

Literature Corpus work

02bc7908-74c4-50ad-94e5-4f1eccff49df

DOI

10.25560/80128