Structural insights into the distinct ligand recognition and signaling of the chemerin receptors CMKLR1 and GPR1

Abstract excerpt

Dear Editor, Chemerin functions as both an adipocytokine and a chemotactic factor and plays key roles in adipogenesis and inflammation (Bozaoglu et al., 2007; Bondue et al., 2011). The chemerin receptors chemokine-like receptor 1 (CMKLR1) and G protein-coupled receptor 1 (GPR1), play crucial roles in regulating obesity, inflammation, and cancer, highlighting their potential as therapeutic targets (Bozaoglu et...

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