Article

Microfluidic bioprinting for the in vitro generation of novel biomimetic human testicular tissues

2021-06-07

Abstract excerpt

Advances in cancer treatments have greatly improved pediatric cancer survival rates, leading to quality of life considerations and in particular fertility restoration. Accordingly, pre-pubertal patients have the option to cryopreserve testicular tissue for experimental restorative therapies, including in vitro spermatogenesis, wherein testicular tissue is engineered in vitro and spermatozoa are collected for in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 02ba8dbe-c078-56d0-b9bc-80e26624facf
DOI: 10.1101/2021.06.04.447126

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Microfluidic bioprinting for the in vitro generation of novel biomimetic human testicular tissuesDOI 10.1101/2021.06.04.447126Read

Advanced bioengineering of male germ stem cells to preserve fertilitySemantic proximity Read

Using clinically derived human tissue to 3-dimensionally bioprint personalized testicular tubules for in vitro culturing: first reportSemantic proximity Read

The Evolutionary Route of in vitro Human Spermatogenesis: What is the Next Destination?Semantic proximity Read

The use of testicular organoids in advancing future treatments for male factor infertilitySemantic proximity Read

Primary Human Testicular Cells Self-Organize into Organoids with Testicular PropertiesSemantic proximity Read

Seminiferous tubule–inspired coaxial bioprinting–derived extracellular vesicles restore Leydig cell steroidogenesis by restraining Wnt4/β-catenin signalingSemantic proximity Read

In‐vitro spermatogenesis through testis modelling: Toward the generation of testicular organoidsSemantic proximity Read

Dynamics, ultrastructure and gene expression of human in vitro organized testis cells from testicular sperm extraction biopsiesSemantic proximity Read

Organoids of the male reproductive system: Challenges, opportunities, and their potential use in fertility researchSemantic proximity Read

Development and evaluation of a microfluidic human testicular tissue chip: a novel in vitro platform for reproductive biology and pharmacology studiesSemantic proximity Read

A Novel Organoid Model of In Vitro Spermatogenesis Using Human Induced Pluripotent Stem CellsSemantic proximity Read

3D Bioprinting of Collagen-based Microfluidics for Engineering Fully-biologic Tissue SystemsSemantic proximity Read