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Advanced bioengineering of male germ stem cells to preserve fertility

1 Jan 2021

Abstract excerpt

In modern life, several factors such as genetics, exposure to toxins, and aging have resulted in significant levels of male infertility, estimated to be approximately 18% worldwide. In response, substantial progress has been made to improve in vitro fertilization treatments (e.g. microsurgical testicular sperm extraction (m-TESE), intra-cytoplasmic sperm injection (ICSI), and round spermatid injection (ROSI))....

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PMID: 34868541
DOI: 10.1177/20417314211060590

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