Article
A Novel Organoid Model of In Vitro Spermatogenesis Using Human Induced Pluripotent Stem Cells
2021-06-07
Abstract excerpt
Infertility is thought to be caused by genetic mutations and dysfunction in the cellular niche where spermatogenesis takes place. An understanding of the specialized cellular processes which drive spermatogenesis is needed to develop treatments; however, the development of in vitro systems to study these cells has been hindered by our reliance on rarely available human testicular tissues for research. Human induc...
Topics
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- Animal Genetics and Reproduction
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Pluripotent Stem Cells Research
- Renal and related cancers
- Reproductive Biology and Fertility
- Sexual Differentiation and Disorders
- Sperm and Testicular Function
- Testicular diseases and treatments
Identifiers and source
- Literature Corpus work
- a7b3be0d-1d45-5458-b63f-6598b3a2d446
- DOI
- 10.1101/2021.06.04.447122
