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The Evolutionary Route of in vitro Human Spermatogenesis: What is the Next Destination?

29 Apr 2024

Abstract excerpt

Malfunction in spermatogenesis due to genetic diseases, trauma, congenital disorders or gonadotoxic treatments results in infertility in approximately 7% of males. The behavior of spermatogonial stem cells (SSCs) within three-dimensional, multifactorial, and dynamic microenvironment implicates a niche that serves as a repository for fertility, since can serve as a source of mature and functional male germ cells....

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PMID: 38684571
DOI: 10.1007/s12015-024-10726-2

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